The Dallas Cowboys and Philadelphia Eagles resume their longtime NFL East Division rivalry on Sunday night, with first place on the line.
The Eagles, the lone undefeated team at 5-0, will play host to the Cowboys (4-1), who are on a four-game winning streak. Dallas leads the all-time series, which began in 1960, 72-54.
And for you fantasy football players, this is the first week of byes so adjust your rosters accordingly.
Here’s everything you need to know about the NFL odds for Week 6 — the point spread, moneyline and total over/under (with all NFL odds via FOX Bet).
Teams with a bye: Lions, Raiders, Texans, Titans
All times ET
THURSDAY’S GAME
Commanders at Bears (8:15 p.m., Amazon Prime Video)
Point spread: Bears -1 (Bears favored to win by more than 1 point, otherwise Commanders cover)
Moneyline: Bears -110 co-favorites to win (bet $10 to win $19.09 total); Commanders -110 co-favorites to win (bet $10 to win $19.09 total)
Total scoring over/under: 37.5 points scored by both teams combined
RELATED: How to bet Commanders-Bears
Jalen Hurts, Eagles defeat Cardinals to move to 5-0, will face Cowboys in Week 6 | UNDISPUTED
Jalen Hurts and the Philadelphia Eagles remain the only undefeated team in the league after beating the Arizona Cardinals.
SUNDAY’S GAMES
49ers at Falcons (1 p.m., FOX)
Point spread: 49ers -5.5 (49ers favored to win by more than 5.5 points, otherwise Falcons cover)
Moneyline: 49ers -250 favorites to win (bet $10 to win $14 total); Falcons +190 underdogs to win (bet $10 to win $29 total)
Total scoring over/under: 44.5 points scored by both teams combined
RELATED: How to bet 49ers-Falcons
Patriots at Browns (1 p.m., CBS)
Point spread: Browns -2.5 (Browns favored to win by more than 2.5 points, otherwise Patriots cover)
Moneyline: Browns -143 favorites to win (bet $10 to win $16.99 total); Patriots +110 underdogs to win (bet $10 to win $21 total)
Total scoring over/under: 43.5 points scored by both teams combined
RELATED: How to bet Patriots-Browns
Point spread: Packers -7 (Packers favored to win by more than 7 points, otherwise Jets cover)
Moneyline: Packers -333 favorites to win (bet $10 to win $13 total); Jets +250 underdogs to win (bet $10 to win $35 total)
Total scoring over/under: 45.5 points scored by both teams combined
RELATED: How to bet Jets-Packers
Jaguars at Colts (1 p.m., CBS)
Point spread: Colts -1.5 (Colts favored to win by more than 1.5 points, otherwise Jaguars cover)
Moneyline: Colts -133 favorites to win (bet $10 to win $17.52 total); Jaguars +105 underdogs to win (bet $10 to win $20.50 total)
Total scoring over/under: 42.5 points scored by both teams combined
Vikings at Dolphins (1 p.m., FOX)
Point spread: Vikings -3.5 (Vikings favored to win by more than 3.5 points, otherwise Dolphins cover)
Moneyline: Vikings -175 favorites to win (bet $10 to win $15.71 total); Dolphins +135 underdogs to win (bet $10 to win $23.50 total)
Total scoring over/under: 45.5 points scored by both teams combined
RELATED: How to bet Vikings-Dolphins
Bengals at Saints (1 p.m., CBS)
Point spread: Bengals -1.5 (Bengals favored to win by more than 1.5 points, otherwise Saints cover)
Moneyline: Bengals -133 favorites to win (bet $10 to win $17.52 total); Saints +105 underdogs to win (bet $10 to win $20.50 total)
Total scoring over/under: 43.5 points scored by both teams combined
RELATED: How to bet Bengals-Saints
Ravens at Giants (1 p.m., CBS)
Point spread: Ravens -5.5 (Ravens favored to win by more than 5.5 points, otherwise Giants cover)
Moneyline: Ravens -250 favorites to win (bet $10 to win $14 total); Giants +190 underdogs to win (bet $10 to win $29 total)
Total scoring over/under: 43.5 points scored by both teams combined
Buccaneers at Steelers (1 p.m., FOX)
Point spread: Buccaneers -8.5 (Buccaneers favored to win by more than 8.5 points, otherwise Steelers cover)
Moneyline: Buccaneers -400 favorites to win (bet $10 to win $12.50 total); Steelers +280 underdogs to win (bet $10 to win $38 total)
Total scoring over/under: 43.5 points scored by both teams combined
RELATED: How to bet Buccaneers-Steelers
Panthers at Rams (4:05 p.m., FOX)
Point spread: Rams -10.5 (Rams favored to win by more than 10.5 points, otherwise Panthers cover)
Moneyline: Rams -500 favorites to win (bet $10 to win $12 total); Panthers +300 underdogs to win (bet $10 to win $40 total)
Total scoring over/under: 40.5 points scored by both teams combined
RELATED: How to bet Panthers-Rams
Cardinals at Seahawks (4:05 p.m., FOX)
Point spread: Cardinals -2.5 (Cardinals favored to win by more than 2.5 points, otherwise Seahawks cover)
Moneyline: Cardinals -149 favorites to win (bet $10 to win $17.71 total); Seahawks +115 underdogs to win (bet $10 to win $21.50 total)
Total scoring over/under: 51.5 points scored by both teams combined
RELATED: How to bet Cardinals-Seahawks
Bills at Chiefs (4:25 p.m., CBS)
Point spread: Bills -2.5 (Bills favored to win by more than 2.5 points, otherwise Chiefs cover)
Moneyline: Bills -149 favorites to win (bet $10 to win $17.71 total); Chiefs +115 underdogs to win (bet $10 to win $21.50 total)
Total scoring over/under: 53.5 points scored by both teams combined
RELATED: How to bet Bills-Chiefs
Cowboys at Eagles (8:20 p.m., NBC)
Point spread: Eagles -6 (Eagles favored to win by more than 6 points, otherwise Cowboys cover)
Moneyline: Eagles -278 favorites to win (bet $10 to win $13.60 total); Cowboys +205 underdogs to win (bet $10 to win $30.50 total)
Total scoring over/under: 42.5 points scored by both teams combined
RELATED: How to bet Cowboys-Eagles
MONDAY’S GAME
Broncos at Chargers (8:15 p.m. ET, ESPN)
Point spread: Chargers -5.5 (Chargers favored to win by more than 5.5 points, otherwise Broncos cover)
Moneyline: Chargers -227 favorites to win (bet $10 to win $14.41 total); Broncos +175 underdogs to win (bet $10 to win $27.50 total)
Total scoring over/under: 45.5 points scored by both teams combined
Our Analysts have you covered on all you need for this weekend’s action!
– Warren Sharp’s Betting Edges
– Patrick Everson’s Sharp Bettor Plays
– Geoff Schwartz’s College Football Best Bets
– Jason McIntyre’s Best NFL Bets
– Geoff Schwartz’s NFL Best Bets
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