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49ers vs Rams odds, predictions, betting trends for NFL’s ‘Monday Night Football’



When the Rams (7-2) are on their way to face the 49ers (3-5) to wrap up NFL Week 10 on “Monday Night Football” (8:15 p.m. ET, ESPN, ESPN2), they’ll be looking to make a further segregated numbers in the NFC West leaderboard. Los Angeles and San Francisco will also renew the rivalry between two NFC championship coaches, Sean McVay and Kyle Shanahan.

The Rams have added wide receiver Odell Beckham Jr to foul their passing with Matthew Stafford and Cooper Kupp. The 49ers showed more through the air with George Kittle returning to help Jimmy Garoppolo, Deebo Samuel and Brandon Aiyuk. Both teams will also look to run well with Darrell Henderson and rookie Elijah Mitchell.

Here’s everything there is to know about betting between the 49ers vs. Rams in Week 10, including our updated odds, trends and predictions for “Monday Night Football”.

49ers vs Rams Odds for Monday Night Football

  • Transmitted: Rams of 3.5
  • On lower: 50.5
  • Moneyine: Rams -186, 49ers +156

The Rams started out as the favorites but as the week progressed, the number dropped to close to a pitch goal due to a number of developments, including the healthier looking 49ers and the Rams losing their referee recipient. widely Robert Woods for an ACL that was torn through the end of the season over the weekend.

(betting odds per FanDuel Sportsbook)

The All Time Series 49ers vs. Rams

The 49ers still have a 73-67-3 lead. They increased their advantage by winning four consecutive games, wiping out the Rams in both 2019 and 2020. Before that, the Rams won 3/4 matches. The last three meetings were decided by one owner.

Three trends to know

—88 percent of bettors prefer the 49ers to cover the spread as nighttime losers, given how much later their offense comes.

—56 percent of over/under bettors think a high total is still not enough because of the potential for two strong offenses.

—The Rams are 4-6 to the odds and 7-3 in a row in their past 10 games including knockouts. Total passed 6 of those games. The 49ers are 4-6 SU and ATS in the past 10 games. The total also surpassed 6 of those games.

Three things to see

How much will OBJ play?

Without Woods and with Beckham still learning the books, expect the Rams to have more Cooper Kupp and Van Jefferson in the wide opening, while also attracting more Tyler Higbee’s involvement. They should also incorporate their backs more in the passing game.

Will the 49ers run the ball well?

Mitchell got better all-round with haste and received as a rookie. Now that the game is on its way to being more dangerous with Kittle, Samuel and Aiyuk, the 49ers can return to their bread and butter as an extra support for their struggling defence. Performance on the field will keep them in the game.

Who will recover better, Stafford or Jimmy G?

Stafford had his worst game of the season against the Titans, throwing a six pick. Garoppolo did some great plays but also fought against the Cardinals. Count on Stafford as overworked on a depleted secondary team compared to Garoppolo facing Jalen Ramsey and Aaron Donald.

Important Stats

131.6. That’s the average javelin 49 players quit per game, placing it 26th in the NFL. Lowering Woods and breaking Beckham, the Rams need to focus on running on San Francisco with a combination of Darrell Henderson and Sony Michel. It will also take great pressure off the pass guard and Stafford, while playing away from Shanahan’s powerful attack.

Predict 49ers vs Rams

The Rams will not run away from rivals in their division. The 49ers are too well trained to continue to lackluster play at home, where they have struggled to win at any point of the late day. Except for a typical divisional game because the attack outputs will be done closer to the weapons being more uniform.

Rams 24, 49ers 20





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