Health

Why did the FDA approve the generic version of this dangerous drug?


By Dr. Mercola

Actos – the brand name of a drug used to treat type 2 diabetes – is currently embroiled in thousands of lawsuits alleging that the drug causes serious side effects including heart failure, macular edema and macular edema. bladder cancer.

Even so, the US Food and Drug Administration (FDA) went ahead and approved Mylan Lab’s plan to sell a generic version of this dangerous drug (pioglitazone), justifying its rationale. them by saying that this gives patients “reasonable treatment options”.

The FDA has addressed the possibilities of heart failure and bladder cancer with recommendations that doctors carefully monitor patients taking the new generic version…however, what the new generic drug actually does. is causing many people to suffer from ‘unacceptable, and sometimes fatal, conditions. , side effects – to treat a disease that responds very well to changes in diet and exercise!

Actos and its general problems with serious health risks

Actos works by helping to control blood sugar in people with type 2 diabetes, a method that “experts” say will help reduce the long-term health complications of diabetes and keep it under control. sick.

But diabetes treatments that focus solely on lowering blood sugar may actually exacerbate, rather than correct, the underlying metabolic dysfunction at the root of type 2 diabetes. And along with completely ignoring the underlying reasons why diabetes develops in the first place, Actos carries some very serious health risks.

For starters, Actos has a Boxed Warning that says the drug can cause or worsen heart failure.

This risk has been somewhat overshadowed by the attention paid to Avandia, a similar diabetes drug in the same class that has been found to increase the risk of heart attack by 43% and the risk of cardiac death by 64%. pulse, compared with treated patients. with other methods.first However, although Actos is considered a “safer” option for your heart than Avandia, it also poses serious risks to your heart.

And that’s not all.

The Actos label also notes that using pioglitazone for more than one year may increase the risk of bladder cancer. In fact, new research from the University of Pennsylvania’s Perelman School of Medicine shows that people who take the drug for 5 years or more are 2 to 3 times more likely to develop bladder cancer than those who take a form of the drug. other diabetes. drug.2 

Actos has been removed from the market in both Germany and France due to the risk of bladder cancer… but in the US we don’t just have Actos but a generic version too!

Contrary to the story, two days before the FDA approved Mylan’s generic Actos, Watson Pharmaceuticals sued the FDA for failing to follow through with giving Watson exclusive rights to its generic version of Actos, which was originally scheduled for release. on August 17th.

There are about 13,000 Actos lawsuits currently pending, involving both heart failure and bladder cancer, as well as other side effects including bone fractures and lactic acidosis.

Actos Whistleblower reveals fraud, deception and grave danger

Dr. Helen Ge works for Takeda (manufacturer of Actos) in the company’s pharmacovigilance division. There, Dr. Ge was in charge of reviewing the side effects of Actos reported by patients and doctors. She then prepares safety reports to submit to the FDA – reporting that Ge said she was ordered to either refuse or not to report at all, so Actos would look safer than it really is.

She believes that Actos is even more More dangerous than Avandia, the diabetes drug mentioned earlier was removed from pharmacies because of the risk of heart attacks. Dr Ge says that in addition to bladder cancer and tumours, Actos has been linked to heart attacks and strokes, suicide, schizophrenia, attempted murder and kidney failure.

Dr. Ge filed a lawsuit in September 2011, alleging that Takeda, like many pharmaceutical companies, was primarily concerned with protecting their profits, which made approving a generic version of the drug This drug is becoming more and more worrisome. Actos is Takeda’s most profitable drug, bringing in $3.4 billion in annual sales.

Dr. Ge notes:3

“Takeda’s motives for reporting fraud and underreporting serious adverse events were driven by an economic desire to enhance Actos’ safety profile bias and increase sales.”

So far Avandia has been Children’s posters for what is wrong with the type 2 diabetes drug. And it took nearly 10 years since the drug was on the market for the FDA to take action and restrict access to the drug. this dangerous drug. Meanwhile, millions of people have taken Avandia and suffered unacceptably high-risk side effects, for a drug that in no way treats the underlying causes of diabetes.

More than 80,000 diabetics have suffered strokes, heart failure or other complications including deadly heart attacks as a result of this dangerous drug… and now it comes Actos and its generic versions. will probably replace it.

Things You Should Know About Diabetes Pills…

Drug can not cure diabetes, as they do nothing to address the underlying cause. Drugs like Actos and Avandia work by tricking diabetics’ bodies into becoming more sensitive to their own insulin, which helps control blood sugar. Trick the body in ways that are not ancestral, and the time that our biochemistry and genetics have adjusted to with age often leads to devastating ultimately devastating effects if pursued long enough, and experienced of Actos and Avandia confirm this.

But it’s important to understand that diabetes is NOT strictly a blood sugar disease as your doctor may have led you to believe. Type 2 diabetes is actually a disease caused by insulin resistance and faulty leptin signaling (a relatively recently discovered hormone produced by fat), both of which are regulated through via your diet.

Conventional treatment, which focuses on preventing symptoms of high blood sugar rather than addressing the underlying causes, will fail in most cases.

Because type 2 diabetes arises due to faulty leptin and insulin signaling, it is therefore a completely preventable condition and can be controlled or reversed by recuperate your sensitivity to insulin and leptin. However, the only known effective long-term way to re-establish proper leptin and insulin signaling is through proper diet and exercise. There is NO drug that can safely do this – a fact that makes the current pattern of disease even more tragic, as diabetes continues to soar and conventional treatments fail. necessary to kill diabetics early.

If you have type 2 diabetes, I strongly recommend consulting with a healthcare practitioner who understands its true underlying cause and who can work with you to reverse the condition without the use of drugs. Some of the most helpful guidelines for doing this successfully include:

  • Limit or severely eliminate sugars and grains from your diet, especially fructose, which is far more harmful than any other sugar. Following my Nutrition Plan will help you do this without too much fuss.
  • Exercise regularly. Exercise is an extremely necessary element, and without it, you can hardly control this terrible disease. This is one of the fastest and most effective ways to reduce insulin and leptin resistance. I recommend including some intense Peak Fitness workouts for optimal results.
  • Avoid synthetic trans fats.
  • Get plenty of omega-3 fats from high-quality animal sources, such as krill oil.
  • Optimizing vitamin D levels. Recent studies have revealed that getting enough vitamin D can also have a powerful effect on normalizing your blood pressure, helping to improve a near-identical response to other conditions. diabetes interventions.
  • Optimize your gut microbiome. Your gut is a living ecosystem, filled with many different types of bacteria. The more beneficial bacteria you have, the more balanced your blood sugar will be. Indeed, new research published in the journal Lipids in health and disease found that a combination of prebiotics and probiotics, taken for 30 days, significantly reduced fasting blood sugar in humans.4

Fortunately, optimizing your gut microbiome is relatively easy. You can replenish your good bacteria by eating fermented foods (like natto, kefir, raw organic cheeses, miso, and fermented vegetables) or by taking a high-quality probiotic supplement.

  • Address any underlying emotional and/or stressful issues. Non-invasive tools like the Emotional Freedom Technique (EFT) can be extremely helpful and effective.
  • Get enough sleep every night.
  • Monitor your fasting insulin levels. This is just as important as your fasting blood sugar. You’ll want your fasting insulin level to be between 2 and 4. The higher the level, the worse your insulin sensitivity.





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