Health

Rhonda Patrick on Vitamin C


This article was previously published on June 6, 2020 and has been updated with new information.

Vitamin C, a water-soluble vitamin found abundantly in fruits and vegetables, is an essential nutrient that humans must get from diet or supplements. Also known as ascorbic acid, vitamin C is perhaps best known for its antioxidant properties – a property it maintains through its ability to donate electrons to oxidized molecules.

In the video above, Dr. Rhonda Patrick discusses vitamin C in depth, covering everything from its effects on immune function and viral infections to the bioavailability of the vitamin’s forms and uses. C varies, such as oral or intravenous – plus more. If you want to learn how vitamin C can benefit your health, this video is a must-see.

Vitamin C has many roles in your health

Vitamin C, even in small amounts, protects proteins, lipids and even the DNA and RNA in your body from reactive oxygen species produced during normal metabolism as well as from toxin exposure. (such as cigarette smoke and air pollution).

According to Patrick, vitamin C is also involved in the biosynthesis of collagen, carnitine and catecholamines. main processes and pathways. “first

Intravenous (IV) vitamin C has also shown promise in helping to treat viral infections and cancer, and vitamin C is also involved in how your body processes other vitamins, such as vitamins. E, it regenerates from the oxidized form. Vitamin C also makes iron from food sources more biologically valuable because it enhances the absorption of nonheme iron in the intestines.2

Vitamin C and Immune Function

The role of vitamin C in immune function is of great interest. “It stimulates the production of white blood cells, especially neutrophils, lymphocytes and phagocyts, and promotes normal cellular functions, such as the ability to develop,” says Patrick. reveal, migrate, and engulf pathogens.3

Vitamin C also acts as an antioxidant in your cells, helping to protect immune cells from damage and possibly promoting the production of interferon, which helps protect against viruses.

There is also evidence that vitamin C may help in some cases of exercise-induced immune dysfunction. While exercise is generally beneficial for immune function, over-exercising or repetitive high-intensity exercise can affect the immune system. For example, in the case of marathon runners, skiers and soldiers, those taking vitamin C supplements were 50% less likely to catch colds.4

The anti-cold effect of vitamin C is one of the most well-researched, and research shows that vitamin C prophylaxis as well as treatment at the onset of cold symptoms can reduce symptoms. symptoms and duration of cold.5 It may also be helpful against COVID-19.

In my March 17, 2020 interview with Dr. Andrew Saul, editor-in-chief of Orthomolecular Medicine News Service, he mentioned coming into contact with a Korean medical doctor who was injecting a patient and healthcare workers 100,000 IU of vitamin D along with 24,000 mg (24 grams) of vitamin C.

As explained by Saul, vitamin C in extremely high doses acts as an antiviral, actually killing viruses. Although it has anti-inflammatory activity, which helps block the massive cytokine outflow associated with severe SARS-CoV-2 infection, its antiviral potential may have more to do with its being a rate-limited free radical scavenger.

Patrick also notes that vitamin C can protect against respiratory diseases. In one study, people with the highest levels of vitamin C had a 15% lower risk of respiratory diseases and a 46% lower risk of dying from lung cancer than those with the lowest levels.6

Furthermore, vitamin C, well known for helping to protect the lungs, has new meaning during the COVID-19 pandemic. According to Patrick:7

“The innate immune system of the lungs is an integral component of the body’s defenses, protecting the body against exposure to inhaled oxidants and pathogens… The lung protection of vitamin C is supported by strong data showing that vitamin C intake protects against chronic obstructive pulmonary disease, pulmonary fibrosis, and other respiratory diseases, including lung cancer.

But this feature is of particular relevance because of recent concerns about complications related to COVID-19, such as pneumonia and acute lung injury, which often require ventilatory support.

Observational and epidemiological data indicate that higher vitamin C intake is associated with a reduced risk of developing pneumonia, and this vitamin has also been shown to be effective in reducing the length of time patients are able to breathe. machine, especially in patients who need to be over 24 years old. hourly breathing support. “

Vitamin C and Cancer

Another interesting area of ​​vitamin C research has to do with cancer. Research shows that intravenous vitamin C can prolong survival compared with chemotherapy alone, even for pancreatic and ovarian cancer, which are among the most dangerous cancers. most dangerous. Patrick mentions two studies in pancreatic cancer patients, which showed that intravenous vitamin C reduced tumor size and promoted longer progression-free survival.8

Vitamin C also helps improve the quality of life of cancer patients. In a study of 39 patients diagnosed with terminal cancer, IV vitamin C improved physical, emotional, and cognitive well-being as well as reduced fatigue, nausea, vomiting, pain, and loss of appetite. .9

Since conventional cancer therapies often result in significant side effects, including physical, emotional, cognitive, and sexual impairment, the use of vitamin C as an adjuvant to improve Quality of life can be a significant improvement.

Vitamin C for heart and brain health

Patrick’s video also talks about vitamin C’s role as a cardioprotectant, as well as a mediator for brain health. For starters, vitamin C is known to have a protective effect against high blood pressure, as well as lower blood pressure in people with high blood pressure or prehypertension.ten

Vitamin C also holds promise for treating ischemia and perfusion damage, which can occur after a heart attack or stroke, leading to increased inflammation and oxidative damage. “Vitamin C may be effective in reducing myocardial damage in part by reducing oxidative stress,” explains Patrick.11 In your brain, vitamin C is also essential. According to Patrick:twelfth

“Vitamin C is found in high concentrations in the brain, particularly in the hippocampus and prefrontal cortex – areas involved in the consolidation of memory, learning and aspects of executive function.

In fact, in a classic example of the body aligning resources based on need, the brain retains vitamin C during periods of deficiency at the expense of other tissues. This is vital to our survival: Evidence suggests that vitamin C plays roles in the brain throughout its lifespan from development to adulthood. “

Because of vitamin C’s antioxidant properties, it may help reduce the risk of neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and multiple sclerosis because it reduces oxidative damage. “Vitamin C is also important for the regulation of neurotransmitters, the formation of nerve circuits, and many other important brain functions,” says Patrick.13

Vitamin C as a ‘Heal’

Patrick describes Dr. Linus Pauling’s two-time Nobel Prize-winning publication on vitamin C and the common cold as the driving force that brought vitamin C into the public’s mind as a cure-all. While this is an exaggeration – vitamin C cannot cure everything – what is really remarkable is that many different conditions seem to benefit from vitamin C. In addition to being an antioxidant and Against infections, Patrick describes the benefits of vitamin C for:

Pneumonia

Asthma

Bronchospasm due to exercise

Fatty Acid Oxidation

Sepsis

Myocarditis in children

Herpes

Epstein-Barr virus infection

Fertility and fertility

Inflammation

Lung cancer

Common cold and other respiratory illnesses

The bioavailability of vitamin C varies by form

There is variation in the bioavailability of vitamin C depending on its form. Both the frequency and dosage of vitamin C will affect your levels, but will also affect taking it in oral or IV form.

“For example, oral vitamin C that is absorbed in the small intestine via specialized transporters may be saturated, but intravenous vitamin C will pass through the intestines, achieving blood concentrations and tissue is significantly higher than the oral form”. .14

Vitamin C IV can lead to blood levels up to 70 times higher than equivalent oral doses.15 That being said, liposomal vitamin C, in which vitamin C is enclosed in a lipid bead, can significantly increase the bioavailability of oral vitamin C.

“Several studies have shown that the oral bioavailability of vitamin C may be increased when consumed in liposomal form, creating a unique oral bioavailability profile,” says Patrick. vitamin C or liposomal vitamin C.16

“The mean peak plasma concentration of vitamin C in the participants taking the free form was about 180 micromoles per liter of blood. However, in the liposomal users, the mean peak plasma concentration was 300. micromoles per liter of blood, a 70% difference,” she said.17

I truly believe that liposomal vitamin C is essential for your kit to be cleared for acute viral diseases. If I am very ill, I will take 4 grams of liposomal vitamin C every hour until I feel better, then begin to reduce the dose slowly over several days as my symptoms improve.

Best food sources of vitamin C

I personally only supplement with 100 milligrams (mg) of vitamin C and only if I don’t regularly eat fresh cherries. I have several trees on my property that usually harvest every few weeks for nine months of the year. Each cherry has 80 mg of vitamin C, so I can easily get up to 10 grams on the days I eat cherries.

Many foods are high in vitamin C, including red peppers, parsley, broccoli, kiwi, strawberries, guava, tomatoes, and all citrus fruits. You can get a significant amount of vitamin C from your diet if you eat these foods daily.

However, keep in mind that cooking destroys about 25% of the vitamin C present in foods.18 Fortunately, many foods rich in vitamin C are often eaten raw. If you are healthy, or just mildly ill, you can certainly use these foods and they may even be better, but if you want to treat an illness, it is best to take vitamin C in its form. complementary. liposomal or IV. Furthermore, according to Patrick:19

“It is noteworthy that some scientists believe that compelling evidence supports an increase in the RDA for vitamin C to 200 milligrams per day for adults. The risk of chronic diseases such as heart disease, stroke, cancer, and more mail and metabolic dysfunction.”

Some populations, including those who smoke, drink alcohol, or have inflammatory bowel disease, may need an increase in vitamin C intake, but some studies suggest that vitamin C deficiency may be more common than found.

“Interestingly, a population-based cross-sectional study of nearly 150 patients admitted to a major teaching hospital in Canada found that 60% of patients had suboptimal plasma vitamin C levels and 19% is deficient, with levels roughly equal to those associated with scurvy,” noted Patrick.20 It’s clear that vitamin C is one of those nutrients everyone should make sure to get enough of, but if you’re seriously ill, vitamin C becomes even more important.

“Vitamin C can be especially beneficial for people who are seriously ill, especially those with viral infections, who often have lower blood levels of vitamin C than healthy people,” says Patrick. So, in addition to eating plenty of foods rich in vitamin C daily, take note of vitamin C supplements during illness. Fortunately, Patrick adds, “With some exceptions, oral and intravenous vitamin C supplementation has been shown to be safe, well-tolerated, and low in toxicity.”21





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