Ibuprofen is a common pain reliever and fever reducer. It’s extremely popular, easy to get, and generally safe. However, some people should be aware that combining ibuprofen with other medications can be quite dangerous. A new study at the University of Waterloo has revealed that ibuprofen with diuretics and renin-angiotensin system (RSA) inhibitors for high blood pressure form a dangerous combination for the kidneys – it can cause permanent damage.
Ibuprofen is a very common pain reliever, but extreme caution is required. Image credit: Derrick Coetzee via Wikimedia
Ibuprofen and many similar pain relievers are over-the-counter products, leading some people to automatically believe they are safe. However, scientists have warned people that the drug must always be used with caution and with all appropriate information used. You should always consult your doctor about combining different drugs, even if some of them seem completely innocent to you.
The researchers used computer-simulated drug tests to see how the three drugs interact and the effects on the kidneys. In this case, they looked at ibuprofen, RSA used for high blood pressure, and diuretics. These models reveal that for some people the combination can be quite dangerous – it can cause kidney damage, which in some cases can be permanent.
Anita Layton, one of the study’s authors, said: “Not everyone who happens to take this drug combination will experience problems. But research shows it’s a problem enough that you should be cautious. “
All of these drugs are sometimes used together – they are all quite common. Diuretics force the body to retain less water – essentially, people taking these drugs go to the bathroom more often. This effect manifests itself in the kidneys, which can then be compromised when the drug is combined with ibuprofen. Medications to treat high blood pressure are also quite common and necessary. This means that these people need to be aware of the potential dangers of taking ibuprofen and similar drugs.
Scientists are also very excited about the method itself. Computer modeling allows drug compatibility to be checked without the need for lengthy and expensive tests. Math and computer science can be a good start to studies looking at drug complications in certain circumstances. Because drugs don’t work the same with every health profile.
Ibuprofen seems like a very innocent drug and people often take it without much thought. However, it is still a drug and you should understand that it may interact with other things you take. Consult a medical professional before combining different medications, regardless of whether they are over-the-counter or not. Because permanent kidney damage is as bad as it sounds.
The source: University of Waterloo
